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# 2 ICH Analytical Procedure Guides Available
- URL: https://www.fdaweb.com/2-ich-analytical-procedure-guides-available/
- Published: 2024-03-07T12:00:00.000Z
- Updated: 2026-09-14T14:24:46.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5156508

*Federal Register* notice: FDA is making available two International Council for Harmonization final guidances entitled “Q2(R2) Validation of Analytical Procedures” and “Q14 Analytical Procedure Development.” Q2(R2) provides a general framework for the principles of analytical procedure validation, including validation principles that cover the analytical use of spectroscopic data. Q14 provides harmonized scientific approaches for analytical procedure development and describes principles to achieve more efficient, science-based, and risk-based postapproval change management. “The guidances are intended to facilitate regulatory evaluations and potential flexibility in postapproval change management of analytical procedures when scientifically justified,” FDA says. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2024-03-07/pdf/2024-04834.pdf?ref=fdaweb.com).