> ## Content Index
> Fetch the complete content index at: https://www.fdaweb.com/llms.txt
> Use this file to discover other available public pages before exploring further.

# 2007 FDA Law Brought Better Trial Reporting: Study
- URL: https://www.fdaweb.com/2007-fda-law-brought-better-trial-reporting-study/
- Published: 2018-10-24T12:00:00.000Z
- Updated: 2026-09-15T00:40:15.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5142664

A new study has concluded that the FDA Amendments Act (FDAAA) of 2007 has led to more clinical trials being registered and resulted reported on *ClinicalTrials.gov*. The study, published in [*Trials Journal*](https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-2957-0?ref=fdaweb.com), examined trials that supported FDA approval of new drugs for neuropsychiatric indications, found that “reporting results on *ClinicalTrials.gov* were significantly higher and publication bias was significantly lower after the passage of the FDAAA in 2007, suggesting that the FDAAA likely contributed to the reduction of selective registration and results reporting and to mitigating publication bias. These findings have important implications for understanding the potential impact of the FDAAA, along with other initiatives that may have improved research reporting, and for developing future strategies to improve selective publication and outcome reporting more broadly.”

  
Before FDAAA, the authors said that among 72 positive trials, none were unpublished or were published with a misleading interpretation. “In contrast, among 29 non-positive trials, 10 were not published and seven were published with misleading interpretations,” they wrote. “Post-FDAAA, among 35 positive trials, again none were unpublished and none were published with a misleading interpretation. In addition, among six non-positive trials, none were unpublished and one was published with a misleading interpretation.”