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# 2seventy bio Leukemia Trial Paused
- URL: https://www.fdaweb.com/2seventy-bio-leukemia-trial-paused/
- Published: 2023-06-14T12:00:00.000Z
- Updated: 2026-09-14T18:39:04.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5154691

2seventy bio says Seattle Children’s has paused the Phase 1 trial of the PLAT-08 study of SC-DARIC33 in acute myeloid leukemia following a fatal adverse event. A company [statement](https://ir.2seventybio.com/news-releases/news-release-details/2seventy-bio-announces-clinical-study-pause-plat-08-trial-sc?ref=fdaweb.com) says the study couples 2seventy bio’s DARIC T cell platform with Seattle Children’s expertise in oncology cell therapies in relapsed/refractory acute myeloid leukemia. It is a first-in-human investigation of the DARIC T cell platform. The fatality occurred in the first patient treated at the second dose level in the Phase 1 trial, the company says.