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# Animal Studies for Organ Preservation Devices Guide
- URL: https://www.fdaweb.com/animal-studies-for-organ-preservation-devices-guide/
- Published: 2019-05-08T12:00:00.000Z
- Updated: 2026-09-15T01:25:19.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5144057

*Federal Register* notice: FDA has made available a final guidance entitled “Utilizing Animal Studies to Evaluate Organ Preservation Devices.” The document recommends balancing the ethical principles of replacement, reduction, and refinement as well as regulatory least burdensome principles, with the goal of using the minimum number of animals necessary to generate data to demonstrate device safety. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2019-05-08/pdf/2019-09402.pdf?ref=fdaweb.com).