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# Bulk Drug Substance Listing Reopened for Comments
- URL: https://www.fdaweb.com/bulk-drug-substance-listing-reopened-for-comments/
- Published: 2021-01-08T12:00:00.000Z
- Updated: 2026-09-14T16:41:59.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5148404

*Federal Register* notice: FDA has reopened the comment period for a notice that appeared in the 7/31/2020 *Federal Register* in which FDA identified certain bulk drug substances (active pharmaceutical ingredients) that it has considered and proposes to include or not include on the list of bulk drug substances for which there is a clinical need. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2021-01-08/pdf/2021-00123.pdf?ref=fdaweb.com).