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# CBER Updates List of Proposed Guidances
- URL: https://www.fdaweb.com/cber-updates-list-of-proposed-guidances/
- Published: 2020-06-24T12:00:00.000Z
- Updated: 2026-09-14T16:19:25.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5147088

CBER has updated its [list of guidance documents](https://www.fda.gov/media/120341/download?ref=fdaweb.com) it plans to issue in 2020\. The list totals 28 guidances, including one on “Interacting with the FDA on Complex and Innovative Clinical Trial Designs for Drugs and Biological Products,” and another on “Chemistry, Manufacturing, and Controls Changes to an Approved Application: Certain Biological Products; Guidance for Industry.” In the “tissues and advanced therapies” category, CBER says it plans to issue guidances on “Human Gene Therapy for Neurodegenerative Diseases,” “Considerations for the Development of Human Gene Therapy Products Incorporating Genome Editing,” and “Considerations for the Development of Chimeric Antigen Receptor (CAR) T Cell Therapies.” Sixteen of the proposed 28 documents have already been issued, according to the listing.