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# Clin-Pharm Guide on Antibody-Drug Conjugates
- URL: https://www.fdaweb.com/clin-pharm-guide-on-antibody-drug-conjugates/
- Published: 2022-02-08T12:00:00.000Z
- Updated: 2026-09-14T17:31:39.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5151108

*Federal Register* notice: FDA is making available a draft guidance entitled “Clinical Pharmacology Considerations for Antibody-Drug Conjugates,” which provides recommendations for developing such products. Specifically, the document addresses the agency’s current thinking on bioanalytical methods, dose selection and adjustment, dose- and exposure-response analysis, intrinsic factors, QTc assessments, immunogenicity, and drug-drug interactions. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2022-02-08/pdf/2022-02604.pdf?ref=fdaweb.com).