> ## Content Index
> Fetch the complete content index at: https://www.fdaweb.com/llms.txt
> Use this file to discover other available public pages before exploring further.

# Clinical Trial Enrichment Strategies Guide
- URL: https://www.fdaweb.com/clinical-trial-enrichment-strategies-guide/
- Published: 2019-03-15T12:00:00.000Z
- Updated: 2026-09-15T01:13:14.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5143618

*Federal Register* notice: FDA has made available a final guidance entitled “Enrichment Strategies for Clinical Trials to Support Demonstration of Effectiveness of Human Drugs and Biological Products.” The document provides several types of enrichment strategies and examples of potential clinical trial designs. It also discusses potential regulatory considerations when using enrichment strategies in clinical trials. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2019-03-15/pdf/2019-04815.pdf?ref=fdaweb.com).