> ## Content Index
> Fetch the complete content index at: https://www.fdaweb.com/llms.txt
> Use this file to discover other available public pages before exploring further.

# Dental Issues with Some Buprenorphine Use: FDA
- URL: https://www.fdaweb.com/dental-issues-with-some-buprenorphine-use-fda/
- Published: 2022-01-12T12:00:00.000Z
- Updated: 2026-09-14T17:28:25.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5150913

FDA is warning patients and prescribers about the potential for dental problems associated with buprenorphine drugs dissolved in the mouth to treat opioid use disorder and pain. An agency [statement](https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns-about-risks-dental-problems-associated-buprenorphine-medicines-dissolved-mouth-treat?ref=fdaweb.com) says problems including tooth decay, cavities, dental abscesses/infection, tooth erosion, and, in some cases, total tooth loss, have been reported, even in patients with no history of dental issues.

The agency says patients may lessen their risk of dental problems by taking preventive measures. After the product is completely dissolved, it says, patients should take a large sip of water, swish it gently around their teeth and gums, and swallow, waiting for at least one hour before brushing their teeth after using the drug to avoid damage to the teeth. Patients should also visit a dentist to develop a preventive strategy, including close monitoring by the dentist and regular dental checkups, the notice says.

FDA also issued a [dental safety communication](https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns-about-dental-problems-buprenorphine-medicines-dissolved-mouth-treat-opioid-use-disorder?ref=fdaweb.com) with answers to key questions about the issue.