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# Draft Guide on Adaptive Trial Designs
- URL: https://www.fdaweb.com/draft-guide-on-adaptive-trial-designs/
- Published: 2018-10-01T12:00:00.000Z
- Updated: 2026-09-15T00:35:07.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5142480

*Federal Register* notice: FDA has made available a draft guidance entitled “Adaptive Designs for Clinical Trials of Drugs and Biologics.” The document provides advice on the appropriate use of adaptive designs for clinical trials. It also describes the basic principles for designing, conducting, and reporting the results from an adaptive clinical trial. To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2018-10-01/pdf/2018-21314.pdf?ref=fdaweb.com).