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# Draft Guide on Hypertension Drug Development
- URL: https://www.fdaweb.com/draft-guide-on-hypertension-drug-development/
- Published: 2018-07-16T12:00:00.000Z
- Updated: 2026-09-15T00:19:32.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5141874

*Federal Register* notice: FDA has made available a draft guidance entitled “Hypertension: Conducting Studies of Drugs Treat Patients on a Background of Multiple Antihypertensive Drugs.” The document was developed based on sponsors’ interest in developing drugs intended to treat resistant hypertension, which sponsors have defined as hypertension not adequately controlled by maximally tolerated doses of three or more antihypertensive drugs with different mechanisms of action. To view the notice, [click here](https://www.gpo.gov/fdsys/pkg/FR-2018-07-16/pdf/2018-15092.pdf?ref=fdaweb.com).