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# Draft Guide on Hypogonadotropic Hypogonadism Drugs
- URL: https://www.fdaweb.com/draft-guide-on-hypogonadotropic-hypogonadism-drugs/
- Published: 2018-01-03T12:00:00.000Z
- Updated: 2026-09-14T23:10:41.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5140399

*Federal Register* notice: FDA has made available a draft guidance entitled “Establishing Effectiveness for Drugs Intended to Treat Male Hypogonadotropic Hypogonadism Attributed to Non-Structural Disorders.” The document provides key design considerations, including recommendations for patient enrollment criteria and efficacy endpoints, for clinical trials to establish effectiveness for such drugs. To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2018-01-03/pdf/2017-28337.pdf?ref=fdaweb.com).