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# Draft Guide on Osteoarthritis Structural Endpoints
- URL: https://www.fdaweb.com/draft-guide-on-osteoarthritis-structural-endpoints/
- Published: 2018-08-23T12:00:00.000Z
- Updated: 2026-09-15T00:27:49.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5142183

*Federal Register* notice: FDA has made available a draft guidance entitled “Osteoarthritis: Structural Endpoints for the Development of Drugs, Devices, and Biological Products for Treatment.” The document discusses the underlying pathophysiology and structural progression of osteoarthritis and how these should be considered when proposing clinical trial endpoints. To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2018-08-23/pdf/2018-18214.pdf?ref=fdaweb.com).