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# Drug Reproductive Toxicity Testing Guide
- URL: https://www.fdaweb.com/drug-reproductive-toxicity-testing-guide/
- Published: 2021-05-12T12:00:00.000Z
- Updated: 2026-09-14T16:58:34.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5149305

*Federal Register* notice: FDA has made available a final guidance entitled *S5(R3) Detection of Reproductive and Developmental Toxicity for Human Pharmaceuticals*. The document provides key considerations for developing a testing strategy to identify hazard and characterize reproductive risk for human pharmaceuticals. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2021-05-12/pdf/2021-10017.pdf?ref=fdaweb.com).