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# FDA Approves 2nd mRNA Booster for Some Individuals
- URL: https://www.fdaweb.com/fda-approves-2nd-mrna-booster-for-some-individuals/
- Published: 2022-03-29T12:00:00.000Z
- Updated: 2026-09-14T17:38:32.000Z
- Author: David McFarland
- Tags: Biologics, #legacy-id-D5151470

FDA has authorized a second booster dose of the Pfizer/BioNTech and Moderna Covid-19 vaccines for older people and certain immunocompromised individuals. The agency [says](https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-second-booster-dose-two-covid-19-vaccines-older-and?ref=fdaweb.com) the action will make a second booster shot available to other populations at higher risk for severe disease, hospitalization, and death.

“Emerging evidence suggests that the second dose of an mRNA Covid-19 vaccine improves protection against severe Covid-19 and is not associated with new safety concerns,” FDA says.

The notice says the agency has determined that the known and potential benefits of a second Covid-19 vaccine booster dose with either of the specified vaccines outweigh their known and potential risks in the authorized populations. “The evidence considered for authorization of a second booster dose following primary vaccination and first booster dose included safety and immune response information provided to the agency as well as additional information on effectiveness submitted by the companies,” it says.