> ## Content Index
> Fetch the complete content index at: https://www.fdaweb.com/llms.txt
> Use this file to discover other available public pages before exploring further.

# FDA Unveils Predictive Toxicology Roadmap
- URL: https://www.fdaweb.com/fda-unveils-predictive-toxicology-roadmap/
- Published: 2017-12-06T12:00:00.000Z
- Updated: 2026-09-14T23:05:45.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5140284

The FDA Toxicology Working Group has laid out its Predictive Toxicology Roadmap, a six-part framework for integrating predictive toxicology methods into safety and risk assessments of FDA-regulated products. FDA acting chief scientist **Denise Hinton** writes in an *FDA Voice* online [post](https://blogs.fda.gov/fdavoice/index.php/2017/12/fda-launches-predictive-toxicology-roadmap-to-enable-advances-in-toxicity-testing/?ref=fdaweb.com) with Center for Food Safety and Applied Nutrition senior advisor **Suzanne Fitzpatrick** that the roadmap calls for FDA research to identify data gaps and to support intramural and extramural research to ensure that the most promising technologies are developed, validated, and integrated into the product pipeline. The roadmap also identifies toxicology issues that need addressing for FDA-regulated products and toxicology areas that could benefit from improved predictivity, the two add.

The post says that novel methods such as organs on a chip or mathematical modeling are being developed for toxicity testing that are generating unique opportunities to improve our ability to quickly and more accurately predict potential toxicities and reduce associated risks.

“We expect these advances will help us move products to market faster while preventing products with increased toxicological risk from ever reaching the market,” they write. Moreover, in many cases, these technologies are reducing the need for animal testing, advancing FDA’s long sought goal of refining, reducing, and replacing testing on animals.”

Hinton and Fitzpatrick say the agency will hold a public workshop as part of its efforts to foster opportunities for sharing ideas, discussing new technologies, and highlighting collaborations that are developing and testing new methods.