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# Guidance on Assessing Abuse Potential Drugs
- URL: https://www.fdaweb.com/guidance-on-assessing-abuse-potential-drugs/
- Published: 2017-01-18T12:00:00.000Z
- Updated: 2026-09-14T22:01:14.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5137748

*Federal Register* Notice: FDA has made available a guidance entitled “Assessment of Abuse Potential of Drugs.” The document is intended to assist sponsors of investigational new drugs and applicants for approval of a new drug in evaluating whether their new drug product has abuse potential. Specifically, it provides recommendations for assessing the abuse potential of central nervous system (CNS)-active new drugs. Thus, if a drug substance is CNS-active, the new drug product containing that drug substance will likely need to undergo a thorough assessment of its abuse potential and may be subject to control under the Controlled Substances Act. To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2017-01-18/pdf/2017-01024.pdf?ref=fdaweb.com).