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# Guidance on Nonclinical Testing for Nicotine Products
- URL: https://www.fdaweb.com/guidance-on-nonclinical-testing-for-nicotine-products/
- Published: 2020-10-29T12:00:00.000Z
- Updated: 2026-09-14T16:34:32.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5147982

*Federal Register* notice: FDA has made available a final guidance entitled *Nonclinical Testing of Orally Inhaled Nicotine-Containing Drug Products*. The document provides guidance about the nonclinical information FDA recommends to support development and approval of such products, including electronic nicotine delivery systems intended for smoking cessation and related chronic indications. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2020-10-29/pdf/2020-23999.pdf?ref=fdaweb.com).