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# Guide on Diabetes Trial Endpoints
- URL: https://www.fdaweb.com/guide-on-diabetes-trial-endpoints/
- Published: 2023-05-26T12:00:00.000Z
- Updated: 2026-09-14T18:34:52.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5154549

*Federal Register* notice: FDA is making available a draft guidance entitled “Diabetes Mellitus: Efficacy Endpoints for Clinical Trials Investigating Antidiabetic Drugs and Biological Products.” The document provides recommendations for demonstrating efficacy for drugs that are intended to reduce diabetes-related hyperglycemia (i.e., antihyperglycemic drugs) and to mitigate iatrogenic hypoglycemia associated with diabetes management. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2023-05-26/pdf/2023-11321.pdf?ref=fdaweb.com).