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# Guide on Drug Trial Adaptive Designs
- URL: https://www.fdaweb.com/guide-on-drug-trial-adaptive-designs/
- Published: 2019-12-03T12:00:00.000Z
- Updated: 2026-09-14T15:55:06.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5145629

*Federal Register* notice: FDA has made available a final guidance entitled “Adaptive Designs for Clinical Trials of Drugs and Biologics.” The document provides recommendations on the appropriate use of adaptive designs for drug clinical trials. It describes important principles for designing, conducting, and reporting the results from an adaptive clinical trial. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2019-12-02/pdf/2019-25986.pdf?ref=fdaweb.com).