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# Guide on Oncology Expansion Cohorts
- URL: https://www.fdaweb.com/guide-on-oncology-expansion-cohorts/
- Published: 2022-03-02T12:00:00.000Z
- Updated: 2026-09-14T17:34:49.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5151269

*Federal Register* notice: FDA is making available a final guidance entitled “Expansion Cohorts: Use in First-in-Human Clinical Trials to Expedite Development of Oncology Drugs and Biologics.” The document provides advice on multiple expansion cohort trial designs for investigational oncology drugs. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2022-03-02/pdf/2022-04397.pdf?ref=fdaweb.com).