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# Guide on Product Manufacturing Discontinuance
- URL: https://www.fdaweb.com/guide-on-product-manufacturing-discontinuance/
- Published: 2020-03-31T12:00:00.000Z
- Updated: 2026-09-14T16:09:31.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5146451

*Federal Register* notice: FDA has made available a guidance entitled “Notifying FDA of a Permanent Discontinuance or Interruption in Manufacturing Under Section 506C of the FD&C Act.” The document discusses requirements for manufacturers to provide FDA timely, informative notifications about changes in the production of certain drugs and biological products. To view the notice, click [here](https://s3.amazonaws.com/public-inspection.federalregister.gov/2020-06800.pdf?ref=fdaweb.com).