> ## Content Index
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# Guide on Retroviral Vector-Based Gene Therapies
- URL: https://www.fdaweb.com/guide-on-retroviral-vector-based-gene-therapies/
- Published: 2020-01-31T12:00:00.000Z
- Updated: 2026-09-14T16:01:13.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5145979

*Federal Register* notice: FDA has made available a final guide entitled “Testing of Retroviral Vector-Based Human Gene Therapy Products for Replication Competent Retrovirus During Product Manufacture and Patient Follow-up; Guidance for Industry.” The document provides recommendations on the identification and amount of material to be tested, and general testing methods. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2020-01-30/pdf/2020-01700.pdf?ref=fdaweb.com).