> ## Content Index
> Fetch the complete content index at: https://www.fdaweb.com/llms.txt
> Use this file to discover other available public pages before exploring further.

# Latest Federal Register Notices
- URL: https://www.fdaweb.com/latest-federal-register-notices-121/
- Published: 2017-01-29T12:00:00.000Z
- Updated: 2026-09-14T22:03:30.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5137853

**FDA Confirms Effective Date of Color Additive Addition**  
*Federal Register* Notice: FDA has confirmed a 12/2/2016 effective date for a final rule that appeared in the 11/1/2016 *Federal Register* that amended the color additive regulations to provide for the safe use of titanium dioxide and \[phthalocyaninato (2-)\] copper to color orientation marks for intraocular lenses. To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2017-01-23/pdf/2017-00534.pdf?ref=fdaweb.com).

**Acthar Gel Withdrawn Over Safety/Effectiveness**  
*Federal Register* Notice: FDA has determined that Acthar Gel Synthetic (seractide acetate) injection, 80 units/milliliter (mL) and 40 units/mL, was withdrawn from sale for reasons of safety or effectiveness. The agency will not accept or approve ANDAs that reference the product because of this determination. To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2017-01-23/pdf/2017-01249.pdf?ref=fdaweb.com).

**Comments Sought on PMA Information Collection**  
*Federal Register* Notice: FDA is seeking comments on an information collection extension related to “Premarket Approval of Medical Devices.” To view the notice, click [here](https://www.gpo.gov/fdsys/pkg/FR-2017-01-23/pdf/2017-01188.pdf?ref=fdaweb.com).