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# Latest Federal Register Notices
- URL: https://www.fdaweb.com/latest-federal-register-notices-75/
- Published: 2022-04-03T12:00:00.000Z
- Updated: 2026-09-14T17:39:10.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5151513

**Comments Extended on Carbadox Carcinogenic Concern**  
03/30/2022 *Federal Register* notice: FDA is extending the comment period of a 1/13 *Federal Register* notice seeking input on scientific data and information related to the residue of carcinogenic concern for the new animal drug carbadox. Comments now can be submitted until 6/10\. To view the notice, click [here](https://public-inspection.federalregister.gov/2022-06762.pdf?ref=fdaweb.com).

**Info Collection on Clinical Investigator Disclosures**  
03/29/2022 *Federal Register* notice: FDA has submitted to OMB an information collection extension entitled “Financial Disclosure by Clinical Investigators” (OMB Control Number 0910-0396). FDA’s regulations require that applicants submitting an application that relies on clinical studies must submit a complete list of clinical investigators who participated in a covered clinical study, and must either certify to the absence of certain financial arrangements with clinical investigators (Form FDA 3454) or disclose to FDA the nature of those arrangements and the steps taken by the applicant or sponsor to minimize the potential for bias (Form FDA 3455). To view the notice, click [here](https://public-inspection.federalregister.gov/2022-06661.pdf?ref=fdaweb.com).

**Device Rule Reduces Paper Copy Submissions**  
03/28/2022 *Federal Register* final rule: FDA is amending the medical device regulations to update mailing address information and to reduce (from three to one) the number of copies of certain documents that need to be submitted to FDA. The rule does not impose any new regulatory requirements as it is editorial related and intended to improve the accuracy of the agency’s regulations by removing a submission requirement that is no longer necessary. To view the notice, click [here](https://public-inspection.federalregister.gov/2022-06508.pdf?ref=fdaweb.com).

**Animal Drug Regs Amended for Approvals**  
03/28/2022 *Federal Register* final rule: FDA is amending the animal drug regulations to reflect application-related actions for new animal drug applications and abbreviated new animal drug applications during 10/2021, 11/2021 and 12/2021\. FDA is also making available the basis of approval and environmental review documents, where applicable. Additionally, the animal drug regulations are being amended to improve their accuracy. To view the notice, click [here](https://public-inspection.federalregister.gov/2022-06395.pdf?ref=fdaweb.com).