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# Liquid, Soft Food Drug Vehicle Guidance
- URL: https://www.fdaweb.com/liquid-soft-food-drug-vehicle-guidance/
- Published: 2018-07-24T12:00:00.000Z
- Updated: 2026-09-15T00:21:10.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5141952

FDA has published a draft guidance, *Use of Liquids and/or Soft Foods as Vehicles for Drug Administration: General Considerations for Selection and In Vitro Methods for Product Quality Assessments*, addressing the approaches recommended for suitability determination of vehicles intended for use with specific drug products. The [document](https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM614401.pdf?ref=fdaweb.com) provides: 

- consideration for selection of liquids and/or soft foods as vehicles;
- standardized in vitro methodology and data recommendations for drug product quality assessments to qualify vehicle(s) for drug product administration;
- recommendations to communicate acceptable (qualified) vehicles in drug product labeling.