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# Metastasis-Free Survival Endpoint Guide
- URL: https://www.fdaweb.com/metastasis-free-survival-endpoint-guide/
- Published: 2021-08-09T12:00:00.000Z
- Updated: 2026-09-14T17:09:48.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5149888

*Federal Register* notice: FDA has made available a final guidance entitled *Nonmetastatic Castration-Resistant Prostate Cancer: Considerations for Metastasis-Free Survival Endpoint in Clinical Trials*. The document provides the agency’s expectations for collection, analysis, and reporting of data pertaining to metastasis-free survival. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2021-08-09/pdf/2021-16929.pdf?ref=fdaweb.com).