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# Nitric Oxide Delivery Device Recalled
- URL: https://www.fdaweb.com/nitric-oxide-delivery-device-recalled/
- Published: 2023-07-19T12:00:00.000Z
- Updated: 2026-09-14T18:45:10.000Z
- Author: David McFarland
- Tags: Devices, #legacy-id-D5154908

NOxBOX has recalled its NOxBOXi Nitric Oxide Delivery System due to a check valve misalignment in the device’s manifold, which may cause it to malfunction. “The device may also change gas cylinders earlier than expected or not at all,” a [recall notice](https://www.fda.gov/medical-devices/medical-device-recalls/noxbox-ltd-recalls-noxboxi-nitric-oxide-system-manifold-failure-may-cause-gas-leaks-and-interrupt?ref=fdaweb.com) says. “This issue may lead to interrupted nitric oxide therapy, causing a drop in blood oxygen levels (desaturation) or increased pressure in the artery that carries oxygen from the heart to the lungs (pulmonary artery) which may pose even greater risks to neonates with congenital heart disease.” The notice says that the device malfunction could cause serious injury or death in an already fragile patient population. The company says that at this time there have been no injury reports related to the issue.