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# OND Custom Medical Queries Are Useful: Article
- URL: https://www.fdaweb.com/ond-custom-medical-queries-are-useful-article/
- Published: 2025-09-30T12:00:00.000Z
- Updated: 2026-09-14T15:22:58.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5159961

FDA researchers say that while much more work is needed, the Office of New Drugs (OND) specialized term grouping system for adverse event analysis, known as OND Custom Medical Queries (OCMQ), has been useful in premarket drug safety evaluation. Writing in the open-source journal *Drug Safety*, the researchers [say](https://link.springer.com/article/10.1007/s40264-025-01582-1?utm%5Fmedium=email&utm%5Fsource=govdelivery) that OCMQs are intended to capture clinically meaningful groupings (safety signals) represented in premarketing data. They say the queries have improved the OND’s ability to detect safety signals and to distinguish and quantify adverse reactions in clinical trial data.