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# Ortho Dermatologics Tretinoin Lotion Approved
- URL: https://www.fdaweb.com/ortho-dermatologics-tretinoin-lotion-approved/
- Published: 2018-08-24T12:00:00.000Z
- Updated: 2026-09-15T00:27:58.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5142194

FDA has approved an Ortho Dermatologics NDA for Altreno (tretinoin 0.05%) lotion, indicated for the topical treatment of acne vulgaris in patients nine years of age and older. Altreno is the first formulation of tretinoin in a lotion, according to the company. In clinical trials, the lotion demonstrated proven efficacy of tretinoin, a retinoid, in a generally well-tolerated formulation with skin dryness, pain, swelling, irritation and peeling reported in less than 4% of patients, it says.