> ## Content Index
> Fetch the complete content index at: https://www.fdaweb.com/llms.txt
> Use this file to discover other available public pages before exploring further.

# Positive Covid Test Requirement Lifted on 2 Therapeutics
- URL: https://www.fdaweb.com/positive-covid-test-requirement-lifted-on-2-therapeutics/
- Published: 2023-02-01T12:00:00.000Z
- Updated: 2026-09-14T18:14:13.000Z
- Author: David McFarland
- Tags: Drugs, #legacy-id-D5153673

FDA says individuals can now be prescribed two Covid-19 therapeutics without having a positive test result showing Covid-19 infection. In a 2/1 notice, the agency says the emergency use authorizations for Pfizer’s Paxlovid and Merck’s Lagevrio have been amended to reflect this flexibility.

The agency notice says that in “rare instances, individuals with a recent known exposure (e.g., a household contact) who develop signs and symptoms consistent with Covid-19 may be diagnosed by their health care provider as having Covid-19 even if they have a negative direct SARS-CoV-2 viral test result. In such instances, their health care provider may determine that treatment with authorized therapeutics may be appropriate if the patient reports mild-to-moderate symptoms of Covid-19 and is at high risk for progression to severe Covid-19, including hospitalization or death, and the terms and conditions of the product’s authorization are met.”

More information about Covid-19 therapeutics can be found on [FDA’s EUA webpage](https://lnks.gd/l/eyJhbGciOiJIUzI1NiJ9.eyJidWxsZXRpbl9saW5rX2lkIjoxMDAsInVyaSI6ImJwMjpjbGljayIsImJ1bGxldGluX2lkIjoiMjAyMzAyMDEuNzA4MjEzMzEiLCJ1cmwiOiJodHRwczovL3d3dy5mZGEuZ292L2VtZXJnZW5jeS1wcmVwYXJlZG5lc3MtYW5kLXJlc3BvbnNlL21jbS1sZWdhbC1yZWd1bGF0b3J5LWFuZC1wb2xpY3ktZnJhbWV3b3JrL2VtZXJnZW5jeS11c2UtYXV0aG9yaXphdGlvbj91dG1fbWVkaXVtPWVtYWlsJnV0bV9zb3VyY2U9Z292ZGVsaXZlcnkjY292aWRkcnVncyJ9.CBXW%5FSxxtmdHEYGI86zat1LDvWPvmoUjkVTzeupPYMs/s/1255720147/br/153803852730-l?ref=fdaweb.com).