> ## Content Index
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# Therapeutic Protein Drug-Drug Interactions Guide
- URL: https://www.fdaweb.com/therapeutic-protein-drug-drug-interactions-guide/
- Published: 2023-06-05T12:00:00.000Z
- Updated: 2026-09-14T18:36:10.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5154614

*Federal Register* notice: FDA is making available a final guidance entitled “Drug-Drug Interaction (DDI) Assessment for Therapeutic Proteins.” The document is intended to help stakeholders determine the need for DDI studies for a therapeutic protein using a systematic, risk-based approach. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2023-06-05/pdf/2023-11900.pdf?ref=fdaweb.com).