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# Updated CVM Guide on Antimicrobial Resistance Risks
- URL: https://www.fdaweb.com/updated-cvm-guide-on-antimicrobial-resistance-risks/
- Published: 2022-12-16T12:00:00.000Z
- Updated: 2026-09-14T18:10:06.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5153417

FDA has issued a draft update to guidance for industry #152, “[Evaluating the Safety of Antimicrobial New Animal Drugs with Regard to Their Microbiological Effects on Bacteria of Human Health Concern](https://www.fda.gov/regulatory-information/search-fda-guidance-documents/cvm-gfi-152-evaluating-safety-antimicrobial-new-animal-drugs-regard-their-microbiological-effects?ref=fdaweb.com).” The guidance is intended to help stakeholders assess antimicrobial resistance (AMR) risks in people due to use of medically important antimicrobial drugs in food-producing animals. The agency says updates include revisions to the risk assessment framework, updated ranking criteria for determining the degree of medical importance of antimicrobial drug classes, and a revised ranking of antimicrobial drug classes as critically important, highly important, or important based on the newly updated ranking criteria (Appendix A).