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# Workshop on Pediatric Complex Trial Designs
- URL: https://www.fdaweb.com/workshop-on-pediatric-complex-trial-designs/
- Published: 2021-08-05T12:00:00.000Z
- Updated: 2026-09-14T17:09:25.000Z
- Author: David McFarland
- Tags: FDA Policy/General, #legacy-id-D5149870

*Federal Register* notice: FDA has announced a public workshop entitled “Advancing the Development of Pediatric Therapeutics Complex Innovative Trial Design.” The agency says that complex and innovative trial designs have the potential to optimize drug development in small populations. Innovations that have been proposed include Bayesian and other methods of utilizing external historical information from previous pediatric trials or other populations (such as adults), adaptive designs, bridging biomarkers, etc. These designs tend to require more extensive discussion and collaboration between drug developers and regulators to implement effectively. To view the notice, click [here](https://www.govinfo.gov/content/pkg/FR-2021-08-05/pdf/2021-16709.pdf?ref=fdaweb.com).