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Novo Nordisk intensifies pressure against Eli Lilly under a motion seeking a preliminary injunction to stop Eli Lilly's “misleading” GLP-1 advertising campaigns while an earlier Novo Nordisk lawsuit proceeds.

latest-news

CBER recently used a virtual town hall to urge developers of cell and gene therapies to take advantage of early engagements with the agency well before a BLA filing to help avoid delays and common regulatory pitfalls. According to a just posted transcript, officials from CBER's Office of Therapeutic Products (OTP) outlined best practices for preparing BLA submissions, with a particular focus on first-time applicants developing advanced therapies.

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Novo Nordisk Seeks Preliminary Injunction Against Lilly

Novo Nordisk intensifies pressure against Eli Lilly under a motion seeking a preliminary injunction to stop Eli Lilly's “misleading” GLP-1 advertising campaigns while an earlier Novo Nordisk lawsuit proceeds.

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CBER Offers Tips for Cell/Gene Therapy BLA Submissions

CBER recently used a virtual town hall to urge developers of cell and gene therapies to take advantage of early engagements with the agency well before a BLA filing to help avoid delays and common regulatory pitfalls. According to a just posted transcript, officials from CBER's Office of Therapeutic Products (OTP) outlined best practices for preparing BLA submissions, with a particular focus on first-time applicants developing advanced therapies.

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FDA Urges Broader Eligibility for Cancer Clinical Trials

An FDA final guidance encourages sponsors of oncology clinical trials to broaden eligibility criteria by including more patients with reduced performance status.

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Final Guidance on Washout Periods in Cancer Clinical Trials

FDA encourages cancer clinical trial sponsors to adopt more flexible eligibility criteria related to washout periods and concomitant medications.

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Animal Drugs

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medical-devices
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Petition Urges FDA to Restrict Antibiotic Use in Animals

A coalition of 65 health, environmental, consumer, farming, and animal welfare organizations petition FDA to withdraw approvals for the routine use of...

medical-devices
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FDA Authorizes 1st Generic Animal Drug for New World Screwworm

FDA authorizes Felix Pharmaceuticals’ generic nitenpyram tablets to treat New World screwworm infestations in dogs and cats.

medical-devices
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Open Letter to Trump Urges FDA Push on Rare Diseases

In an opern letter to president Trump, rare disease advocates urge him to push FDA to accelerate approvals for treatments targeting fatal genetic diso...

medical-devices
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FDA Guide on Developing Drugs for Pulmonary Tuberculosis

FDA posts updated guidance outlining how drugmakers should design clinical development programs for new tuberculosis treatments, emphasizing the need ...

Biologics

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medical-devices
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CBER Offers Tips for Cell/Gene Therapy BLA Submissions

CBER recently used a virtual town hall to urge developers of cell and gene therapies to take advantage of early engagements with the agency well befor...

medical-devices
Read More
J&J Reports Positive Data From Multiple Myeloma Study

Johnson & Johnson reports promising topline results from the three-arm investigational Phase 3 MonumenTAL-6 study evaluating Tecvayli (teclistamab-cqy...

medical-devices
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Dyne Therapeutics BLA for Duchenne Muscular Dystrophy

FDA accepts for priority review a Dyne Therapeutics BLA for zeleciment rostudirsen for treating individuals with Duchenne muscular dystrophy amenable ...

medical-devices
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Blood Donor Screening in an Ebola Outbreak

FDA publishes a guidance notifying blood establishments about agency recommendations for screening and deferring blood donors in response to an Ebola ...

FDA General

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medical-devices
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FDA Advisers Back Expanded Access to Several Compounded Peptides

An FDA advisory committee 7/23 voted to recommend allowing several controversial peptides to be considered for inclusion on the agency's Section 503A ...

medical-devices
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FDA May Go Months Without Senate-Confirmed Commissioner: Analysis

An analysis by PharmaVoice says FDA could remain without a Senate-confirmed commissioner for months as political and procedural hurdles complicate eff...

medical-devices
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FDA Reform Requires a ‘Whole-of-System’ Strategy: Editorial

A Cureus Journal of Medical Science open-source editorial calls for a rebuilding of the U.S. scientific infrastructure as the only way to successfully...

medical-devices
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House Passes FDA Modernization Act 3.0 for Reducing Animal Testing

The U.S. House of Representatives passes the FDA Modernization Act 3.0 (H.R. 2821), advancing bipartisan legislation intended to accelerate the adopti...

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Federal Register

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FDA Moves to Cement Complete Response Letter Transparency Policy

FDA looks to formalize one of its most significant transparency initiatives in decades: the public r...

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FDA Warns Brazilian Drug Maker Over Records Request

FDA sends a Warning Letter to Brazilian over-the-counter drug manufacturer Aeroflex Industria de Aer...

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FDA Delays Review Action on Alzheimer’s Drug

FDA delays by three months its decision on Eisai and Biogen's subcutaneous starting-dose formulation...

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Alnylam Pharma’s Web Promo is Misleading: FDA

FDA sends an untitled letter to Alnylam Pharmaceuticals, citing misleading promotional claims on a c...

Human Drugs

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Novo Nordisk Seeks Preliminary Injunction Against Lilly

Novo Nordisk intensifies pressure against Eli Lilly under a motion seeking a preliminary injunction ...

motusgi
Read More
FDA Urges Broader Eligibility for Cancer Clinical Trials

An FDA final guidance encourages sponsors of oncology clinical trials to broaden eligibility criteri...

motusgi
Read More
Final Guidance on Washout Periods in Cancer Clinical Trials

FDA encourages cancer clinical trial sponsors to adopt more flexible eligibility criteria related to...

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FDA cites Bausch + Lomb Manufacturing Facility

FDA cites Bausch + Lomb for GMP deficiencies following a 3/12-20 inspection of the company's sterile...

Marketing

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FDA Plan Would ‘Fundamentally Reshape’ Drug Ads

Two Sheppard attorneys say an FDA proposal to require complete safety and risk information within th...

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FDA Cites Sanofi Over Misleading Beyfortus Promotional Emails

FDA sends an untitled letter to Sanofi Vaccines U.S., alleging that promotional emails for its respi...

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Friendly Accelerated Approval Disclosures Improve Drug Understanding: Study

A new study suggests that direct-to-consumer prescription drug Web sites may better communicate the ...

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DTC Advertising Industry Braces for Potential End of Adequate Provision

DTC Perspectives CEO Bob Ehrlich warns that an upcoming FDA proposal to eliminate the adequate provi...

Medical Devices

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FDA Early Alert Over Boston Scientific Transcarotid Catheter Systems

FDA issues an early alert warning about a potentially high-risk issue involving certain lots of Bost...

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FDA, Industry Have MDUFA 6 Agreement in Principle

Attorney Jake Leys says MDUFA 6 reauthorization has moved from negotiations into writing the commitm...

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Petition Urges FDA to Create Pathway for Brain-Computer Interfaces

A citizen petition urges FDA to establish a regulatory framework for implantable brain-computer in...

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FDA Selects Dexcom as First Participant in Digital Health Pilot with CMS

FDA names Dexcom as the first participant in its new Technology-Enabled Meaningful Patient Outcomes ...