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FDA posts an unusual internal memorandum detailing how former CDER acting director Tracy Beth Hoeg opposed approval of a Sanofi supplemental BLA for Tzield, only to have her position overturned after her departure from the agency.

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Medical device expert Marcelo Trevino analyzes for Med Device Online the results from the first 100 FDA inspections under the new Quality Management System Regulation.

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Review Memo Dismisses Hoeg’s Block on Tzield Approval

FDA posts an unusual internal memorandum detailing how former CDER acting director Tracy Beth Hoeg opposed approval of a Sanofi supplemental BLA for Tzield, only to have her position overturned after her departure from the agency.

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Data from First 100 QMSR Inspections Analyzed

Medical device expert Marcelo Trevino analyzes for Med Device Online the results from the first 100 FDA inspections under the new Quality Management System Regulation.

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Committee Backs Moderna Flu Vaccine

The FDA Vaccines and Related Biological Products Advisory Committee votes to support Modern’s mRNA flu vaccine mFlusiva.

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FDA Wants Testosterone Therapy Labels Updated

HHS says FDA is seeking labeling changes for testosterone replacement therapy products to reflect current scientific and clinical evidence.

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Animal Drugs

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Petition Urges FDA to Restrict Antibiotic Use in Animals

A coalition of 65 health, environmental, consumer, farming, and animal welfare organizations petition FDA to withdraw approvals for the routine use of...

medical-devices
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FDA Authorizes 1st Generic Animal Drug for New World Screwworm

FDA authorizes Felix Pharmaceuticals’ generic nitenpyram tablets to treat New World screwworm infestations in dogs and cats.

medical-devices
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Open Letter to Trump Urges FDA Push on Rare Diseases

In an opern letter to president Trump, rare disease advocates urge him to push FDA to accelerate approvals for treatments targeting fatal genetic diso...

medical-devices
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FDA Guide on Developing Drugs for Pulmonary Tuberculosis

FDA posts updated guidance outlining how drugmakers should design clinical development programs for new tuberculosis treatments, emphasizing the need ...

Biologics

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medical-devices
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Committee Backs Moderna Flu Vaccine

The FDA Vaccines and Related Biological Products Advisory Committee votes to support Modern’s mRNA flu vaccine mFlusiva.

medical-devices
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Senator Seeks FDA Records on Covid Vaccine Safety Review

Sen. Ron Johnson (R-WI) launches a new investigation into federal handling of Covid-19 vaccine safety issues, seeking records from HHS, FDA and CDC re...

medical-devices
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Expand Some Islet Cell Transplantation Access: Senators

Sens. Shaheen and Collins call on FDA to modify the regulatory pathway for deceased donor islet cell transplantation for some Type 1 diabetes patients...

medical-devices
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FDA Backs Accelerated Pathway for UniQure Huntington's Therapy

FDA tells UniQure that data from its ongoing Phase I/II study of AMT-130 could serve as the primary basis for a BLA seeking accelerated approval for t...

FDA General

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medical-devices
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FDA, MHRA Launch Liaison Program for Regulatory Cooperation

FDA and the UK's Medicines and Healthcare products Regulatory Agency announce a new liaison program designed to strengthen collaboration between the t...

medical-devices
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17 Senate Democrats Hit HHS on FDA, Other Changes

Some 17 Senate Democrats write to HHS secretary Robert F. Kennedy Jr., questioning many of his personnel decisions and expressing concern about the na...

medical-devices
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FDA Cites Formulated Solutions Over Manufacturing, Quality

FDA sends an untitled letter to contract manufacturer Formulated Solutions, citing GMP violations related to component testing and quality oversight a...

medical-devices
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AMA Delegates Call for Tighter FDA Oversight of Unapproved Peptides

Delegates at the American Medical Association's annual meeting vote to support stronger FDA oversight of synthetic peptide products, citing growing co...

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Federal Register

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FDA Warns Brazilian Drug Maker Over Records Request

FDA sends a Warning Letter to Brazilian over-the-counter drug manufacturer Aeroflex Industria de Aer...

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FDA Delays Review Action on Alzheimer’s Drug

FDA delays by three months its decision on Eisai and Biogen's subcutaneous starting-dose formulation...

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Alnylam Pharma’s Web Promo is Misleading: FDA

FDA sends an untitled letter to Alnylam Pharmaceuticals, citing misleading promotional claims on a c...

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PhRMA Urges Changes to FDA’s ‘Plausible Mechanism’ Guidance

PhRMA urges FDA to broaden and clarify its draft guidance on individualized therapies, warning that ...

Human Drugs

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Review Memo Dismisses Hoeg’s Block on Tzield Approval

FDA posts an unusual internal memorandum detailing how former CDER acting director Tracy Beth Hoeg o...

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FDA Wants Testosterone Therapy Labels Updated

HHS says FDA is seeking labeling changes for testosterone replacement therapy products to reflect cu...

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Guide on Immunogenicity Data Submissions for Pharmacokinetic Reviews

FDA releases a guidance that is intended to assist industry in the submission of datasets from clini...

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Grace Therapeutics Preparing NDA Resubmission

Grace Therapeutics says it plans to resubmit its NDA for GTx-104 after receiving an FDA Complete Res...

Marketing

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FDA Cites QOL Medical for Misleading Promotion of Sucraid

FDA issues an untitled letter to QOL Medical, alleging that promotional emails for its rare-disease ...

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FDA Drug Ad Crackdown Leads to More Spending on TV/Streaming Ads: Report

An FDA crackdown on allegedly deceptive prescription drug advertising leads to a sharp increase in p...

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DTC Crackdown Unfazed at Post-Makary FDA: Expert

DTC Perspectives CEO Bob Ehrlich says the sudden departure of former FDA commissioner Marty Makary i...

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Brukinsa TV Ad ‘False or Misleading’: OPDP

A CDER Office of Prescription Drug Promotion Notice of Violation cites a misleading BeOne Medicine T...

Medical Devices

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Data from First 100 QMSR Inspections Analyzed

Medical device expert Marcelo Trevino analyzes for Med Device Online the results from the first 100 ...

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FDA Updates Device READI-Home Innovation Challenge Initiative

FDA posts additional details on its newly launched READI-Home Innovation Challenge, an initiative de...

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Draeger Anesthesia Workstation Correction Expanded

Draeger expands a 10/2024 device correction (Class 1 recall) to include additional Atlan A350 and A3...

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Zoll Medical QSR, MDR Violations

FDA warns Chelmsford, ME-based Zoll Medical about Quality System and Medical Device Reporting violat...