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Human Drugs

Bispecific Antibody Development Guidance

FDA issues a final guidance on regulatory, quality, nonclinical, and clinical considerations for bispecific antibody development programs.

Human Drugs

CDER Wants Firms to Achieve Quality Management Maturity

CDER director Patrizia Cavazzoni says the Center will apply an intense focus to encourage the pharmaceutical industry to achieve quality management ma...

Federal Register

Latest Federal Register Notices

FDA Review posts the Federal Register notices for the week ending 2/21/2021.

Federal Register

Peripheral Vascular Atherectomy Devices

Federal Register notice: FDA makes available a final guidance on premarket submissions for peripheral vascular atherectomy devices.

Human Drugs

Implementing ICH Q12 Postapproval Changes

Federal Register notice: FDA makes available a draft guidance to help implement the ICH Q12: document on postapproval changes.

Medical Devices

Overjet Dental Assist AI Cleared

FDA clears an Overjet 510(k) for its Overjet Dental Assist artificial intelligence product that performs measurement for treating periodontal disease.

Human Drugs

Brukinsa Priority NDA for Marginal Zone Lymphoma

FDA accepts for priority review a BeiGene supplemental NDA for Brukinsa (zanubrutinib) for treating adult patients with marginal zone lymphoma.

Federal Register

More ANDA-specific Bioequivalence Guidances

Federal Register notice: FDA makes available additional draft and revised draft product-specific guidances that provide bioequivalence study design re...

Federal Register

Guide on Device MRI Testing and Labeling

Federal Register notice: FDA makes available a final guidance on Testing and labeling medical devices as MRI-safe.

Medical Devices

CDRH Research on Implant Adverse Events

CDRH announces research efforts it will undertake to address scientific knowledge gaps in host responses to an implanted metal device, including adver...