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FDA General

HHS Overreach Renews Calls for Independent FDA

A Sidley law briefing examines HHSs unprecedented overreach during the Trump Administration, which has drawn increased interest in making FDA an indep...

Human Drugs

Exelixis NDA for Cabometyx/Opdivo Combination

FDA approves an Exelixis NDA for Cabometyx (cabozantinib) in combination with Bristol Myers-Squibbs Opdivo (nivolumab) for treating patients with adva...

Human Drugs

Ultragenyx Cleared for Gene Therapy Trial

FDA gives the green light to Ultragenyx Pharmaceutical to begin a seamless single-protocol Phase 1/2/3 study of UX701, an investigational AAV9 gene th...

Human Drugs

Insys Founder Pays $5 Million Over Opioid Scheme

NJ attorney general Gurbir S. Grewal announces a $5 million settlement with Insys Therapeutics founder John N. Kapoor to resolve allegations that he u...

Medical Devices

MDIC External Evidence Framework Open for Comments

The Medical Device Innovation Consortium says it will receive comments for the next month on its External Evidence Methods Framework.

Biologics

Cell and Gene Therapy Product Manufacturing Considerations

FDA issues a guidance to give manufacturers of licensed and investigational cellular and gene therapy products risk-based recommendations to minimize ...

Human Drugs

sNDA for Esbriet in Lung Disease Gets Priority Review

FDA accepts for priority review a Genentech supplemental NDA for Esbriet (pirfenidone) for treating unclassifiable interstitial lung disease.

Federal Register

New Tobacco Products Applications Guide Withdrawn

Federal Register notice: FDA withdraws a draft guidance entitled Applications for Premarket Review of New Tobacco Products.

Medical Devices

Canon Aquilion Exceed CT System Cleared

FDA clears a Canon Medical Systems 510(k) for the Aquilion Exceed LB CT system.