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Human Drugs

Vertex Pharmas Kalydeco Gains Expanded Indication

FDA approves Vertex Pharmaceuticals Kalydeco (ivacaftor) for use in certain children with cystic fibrosis ages four months to less than six months old...

Human Drugs

FDA OKs Glaxos Nucala for Hypereosinophilic Syndrome

FDA approves GlaxoSmithKlines Nucala (mepolizumab) for adults and children aged 12 years and older with hypereosinophilic syndrome for six months or l...

Human Drugs

RemeGen Breakthrough Status for Disitamab Vedotin

FDA grants RemeGen a Breakthrough Therapy designation for disitamab vedotin (RC48), an anti-HER2 antibody drug conjugate for second-line treatment of ...

Medical Devices

3 Device Accreditation Guidances Issued

FDA publishes three guidances implementing the voluntary pilot for the Accreditation Scheme for Conformity Assessment.

Human Drugs

House Hearing on Unsustainable Drug Prices

The House Oversight and Reform Committee schedules two days of hearings on drug prices with testimony from executives of six companies.

Federal Register

Proposal to Withdraw 5 ANDAs for Lack of REMS

Federal Register notice: FDA proposes to withdraw approval of five ANDAs because the application holders have repeatedly failed to file required annua...

Biologics

Trump May Not Back New FDA Vaccine Guidance

After FDA commissioner Stephen Hahn assured Congress that FDAs review and approval/authorization of a Covid-19 vaccine would be based on data and scie...

Medical Devices

3 Observations in Front Range Laboratory Inspection

FDA releases the FDA-483 with three observations from an inspection at Front Range Laboratories.

Human Drugs

Webinar on Drug QT/Proarrhythmic Risk Assessments

FDA announces a two-day (10/15-16) public Webinar on New Approaches for an Integrated Nonclinical-Clinical QT/Proarrhythmic Risk Assessment.

Medical Devices

High-Risk Groups Should Avoid Amalgam Fillings: FDA

FDA says it now recommends that people in seven high-risk categories refrain from exposure to dental mercury amalgam when possible.