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FDA Aims to Cut Comparative Efficacy Studies for Biosimilars

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FDA proposes a major shift in how biosimilars are evaluated, signaling that many products may no longer need traditional comparati...

Revolution Medicines Wins Orphan Drug Status

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FDA grants Revolution Medicines an orphan drug designation for its investigational therapy daraxonrasib for treating pancreatic ca...

Regeneron Gets Complete Response on Eylea sBLA

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FDA sends Regeneron a complete response letter for its pre-filled Eylea HD syringe supplemental BLA, citing unresolved inspection ...

Multiple Violations at 3 Royal Philips Facilities

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FDA warns Royal Philips, based in the Netherlands, about multiple violations at two of its U.S. medical device manufacturing facil...

Unicycive Plans OLC NDA Resubmission This Year

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Unicycive says it plans to resubmit its NDA for oxylanthanum carbonate to treat hyperphosphatemia before the end of this year.

4 Repeat CGMP Violations at Canadas Innocore

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FDA warns Innocore Sales & Marketing in Woodstock, Ontario, Canada, about CGMP violations in its production of finished drugs.

OND Deputy Named Permanent Director

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FDA names acting Office of New Drugs (OND) director Mary Tran Thanh-Hai as the new OND director, replacing previous head Peter Ste...

Is FDA Lengthening Warning Letter Response Time?

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Three Hyman, Phelps & McNamara attorneys notice that FDA has provided a 30-day response time instead of the usual 15 days for two ...

Dr. Reddys Hit with 7-Item FDA-483

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FDA posts a seven-item Form FDA-483 after inspecting Dr. Reddys Mirfield, West Yorkshire, UK, active pharmaceutical ingredient man...

Intellia Pauses Gene Therapy Phase 3 Trials

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Intellia Therapeutics pauses two Phase 3 trials of nex-z, a CRISPR-based therapy for transthyretin amyloidosis with cardiomyopathy...