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Human Drugs

3rd Circuit Remands Hundreds of Fosamax Cases

The 3rd Circuit Court of Appeals asks a New Jersey federal court to look at hundreds of Fosamax bone fracture cases and determine whether they are pre...

Medical Devices

NeuroOne Thin Film Brain Electrode Cleared

FDA clears a NeuroOne Medical Technologies 510(k) to market its thin film cortical electrode technology for temporary (less than 30 days) recording, m...

Human Drugs

Immunomedics Re-files for Breast Cancer Therapy

Immunomedics resubmits its BLA seeking accelerated approval for sacituzumab govitecan, indicated for treating certain patients with metastatic triple-...

Human Drugs

Merck sBLA Accepted for Keytruda in Bladder Cancer

FDA accepts for priority review a Merck supplemental BLA for Keytruda (pembrolizumab), Mercks anti-PD-1 therapy as monotherapy for treating patients w...

Human Drugs

Lexicon Loses Appeal of FDA Complete Response

FDAs Office of New Drugs denies a Lexicon Pharmaceuticals appeal of a March Complete Response Letter on its NDA for diabetes drug Zynquista (sotaglifl...

Federal Register

Reg Review Period for Ultragenyxs Crysvita

Federal Register notice: FDA determines for patent extension purposes the regulatory review period for Ultragenyxs Crysvita.

Human Drugs

Guide on Clinical Trial Adaptive Designs

FDA releases a final guidance entitled Adaptive Designs for Clinical Trials of Drugs and Biologics.

Human Drugs

Impella Heart Pump Survival Data Favorable: FDA

FDA says that most recent, interim post-approval study results for the Impella RP System continue to show a favorable survival rate compared with pre...

Federal Register

Info Collection on Device Pediatric Subpopulations

Federal Register notice: FDA seeks comments on an information collection extension on a requirement for submitting certain pediatric subpopulation dat...

Federal Register

21 No-longer-marketed ANDAs Withdrawn

Federal Register notice: FDA withdraws approval of 21 ANDAs from multiple applicants after they notified the agency that the drug products were no lon...