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Human Drugs

Clinical Hold on Translate Bios MRT5201

FDA slaps a clinical hold a Translate Bio IND submission for MRT5201 for treating ornithine transcarbamylase deficiency, due to additional clinical an...

Human Drugs

United Imaging Total Body Scanner Cleared

FDA clears a United Imaging 510(k) for the uExplorer total-body scanner, which is described as the worlds first medical imaging scanner that can captu...

Human Drugs

Janssen sBLA for Darzalex in Real Time Review Pilot

Janssen Biotech files the first part of a supplemental BLA for a label expansion to include the use of Darzalex (daratumumab) in combination with lena...

Human Drugs

Panel Deadlocks on Lexicon/Sanofi Diabetes Drug

FDAs Endocrinologic and Metabolic Drugs Advisory Committee votes 8 to 8 on whether to recommend approval for Lexicon Pharmaceuticals Inc and Sanofis s...

Human Drugs

Accelerated Approval Drug Labeling Guidance

FDA issues a guidance to help drug and biological product applicants develop the Indications and Usage section of labeling for products approved under...

Human Drugs

Draft ICH Nonclinical Safety Test Guidance

FDA releases a draft International Council for Harmonization guidance on nonclinical safety testing of pediatric drugs.

Medical Devices

Safety, Performance Based Pathway Guidance

FDA releases a guidance explaining the agencys Safety and Performance Based Pathway as an alternative approach for 510(k) submissions.

Biologics

FDAs Options Against Violative Stem Cell Clinics

Attorney Mark Schwartz explores enforcement options open to FDA following expiration of the enforcement discretion period for stem cell facilities it ...

FDA General

CBS Profiles Furloughed FDA Food Inspector

CBS News profiles an FDA food safety investigator whose care for his autistic son is threatened because he has been furloughed from the agency.

Medical Devices

23andMe Colorectal Cancer Report Cleared

FDA clears a 23andMe 510(k) for the MUTYH-Associated Polyposis report, a genetic health risk report on a hereditary colorectal cancer syndrome.