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Biologics

Priority Review for Tecentriq Plus Chemo in Breast Cancer

FDA accepts for priority review a Genentech supplemental BLA for Tecentriq (atezolizumab) plus chemotherapy for first-line treatment of unresectable l...

Human Drugs

PolyPid IND for Phase 3 Surgery Infection Trial

FDA approves a PolyPid Ltd. IND for it to proceed with a Phase 3 clinical trial involving lead candidate D-Plex[100] for preventing post-cardiac surge...

Federal Register

Info Collection on Device Fees for Small Businesses

Federal Register notice: FDA seeks comments on an information collection extension on a guidance for Medical Device User Fee Small Business Qualificat...

Human Drugs

Global Biotech Development Surge Continues: Tufts Study

A Tufts Center for the Study of Drug Development analysis says the global biotech product development surge that started in the 1980s continues to gro...

Human Drugs

Prostate Cancer Trial Endpoint Guidance

FDA issues a draft guidance on considerations for using a metastasis-free survival endpoint in some prostate cancer drug trials.

Human Drugs

Latest FDA Warning Letters

FDA releases its latest batch of Warning Letters that include StemGenex Biologic Laboratories and U.S. Vascular.

Human Drugs

FDA Accepts Shire sNDA for Pediatric Short Bowel Syndrome

FDA accepts for review a Shire supplemental NDA to expand the indication of Gattex (teduglutide [rDNA origin]) for injection to pediatric patients wit...

Federal Register

Info Collection on IND Sponsor Surveys

Federal Register notice: FDA submits to OMB a new information collection entitled Surveys and Interviews With Investigational New Drug (IND) Sponsors ...

Medical Devices

510(k) Substantial Equivalence Guidance Explained

CDRH biomedical enginer Ifeanyi Uwemedimo explains provisions in a newly-finalized guidance on benefit-risk assessments for 510(k) submissions.

Human Drugs

FDA Wants More Informed Consent Flexibility

FDA says it wants to give institutional review boards some greater flexibility to waive or alter informed consent requirements under some conditions.