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Human Drugs

Arca Biopharma Seeks Special Protocol for Heart Failure Trial

Arca Biopharma submits a special protocol assessment request for its planned Phase 3 clinical development program of Gencaro (bucindolol hydrochloride...

Biologics

FDA Rejects Pharming Expanded Use for Ruconest

FDA issues a Pharming Group complete response letter on its supplemental BLA for Ruconest [C1 esterase inhibitor (recombinant)] to expand the current ...

Medical Devices

Ways to Improve Pediatric Device Development: AdvaMed

AdvaMed gives FDA recommendations for ways to reduce risk in pediatric medical device development.

Medical Devices

Olympus 510(k) for EZ Shot 3 Plus Needle Cleared

FDA clears an Olympus 510(k) for its EZ Shot 3 Plus 25 G needle as well as an expanded indication for the EZ Shot 3 Plus product line for both fine ne...

CTTI Releases Real-World Evidence Meeting Summary

The Clinical Trials Transformation Initiative reports on its public meeting on best practices and needed resources for advancing use of real-world evi...

Medical Devices

Heparin-Containing Device Labeling Guidance

FDA publishes a guidance with labeling and safety testing recommendations for heparin-containing medical devices and combination products.

Human Drugs

Finalize Patient Data Collection Guidance: PhRMA

PhRMA calls on FDA to finalize a draft guidance on collecting patient experience data in a timely manner so the guidance may help drug sponsors.

Human Drugs

Immediate-Release Opioids Now Under REMS

FDA approves a new opioid analgesic REMS that now covers immediate-release products and expands provider education requirements.

Biologics

CBER Planning 16 Guidances for 2018

CBER says it expects to publish 16 guidances under two categories during calendar year 2018.

Medical Devices

Quality System Violations at ITG-Medev

FDA warns ITG-Medev about Quality System violations in its manufacturing of Omiderm wound dressings.