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Medical Devices

FDA Proposing Digital Health Center of Excellence

FDA commissioner Scott Gottlieb and CDRH director Jeffrey Shuren propose a digital health Center of Excellence.

Human Drugs

Liva Pharmaceuticals FDA-483

FDA releases the FDA-483 with five observations from an inspection at Indias Live Pharmaceuticals.

Human Drugs

Praluent sBLA Accepted for Reduced MACE Labeling

FDA accepts for review a Sanofi and Regeneron Pharmaceuticals supplemental BLA for Praluent (alirocumab) to update the Prescribing Information to incl...

Human Drugs

Orphan Status for Syntimmune Pemphigus Therapy

FDA grants Syntimmune an orphan drug designation for SYNT001 for treating pemphigus.

Biologics

Merck sBLA for Keytruda in Lung Cancer

FDA accepts for priority review a supplemental BLA for Keytruda, an anti-PD-1 therapy, as monotherapy for first-line treatment of locally advanced or ...

Human Drugs

ANDA Clinical Study Dataset Guidance

FDA publishes a guidance recommending technical specifications and general considerations for submitting certain ANDA comparative clinical endpoint bi...

Human Drugs

CNS Drugs Longer to Develop, Approve: Tufts Center

A Tufts Center for the Study of Drug Development analysis shows that central nervous system drugs take longer to develop and approve than drugs in oth...

Medical Devices

FDA Finds Violations in 2 Medtronic Inspections

FDA warns two Medtronic manufacturing facilities about Quality System violations in their production of cardiac medical devices.

Medical Devices

Integrate Cybersecurity in Medical Device Reviews: OIG

The HHS Inspector General outlines steps FDA could take to better integrate cybersecurity concerns into its medical device reviews before granting mar...

Federal Register

Panel to Review Pain Drug

Federal Register notice: FDA announces a 10/11 Anesthetic and Analgesic Drug Products Advisory Committee meeting.