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Federal Register

Pilot Meetings for Innovative Trial Designs

Federal Register notice: FDA announces a pilot meeting program to allow sponsors to discuss the use of complex innovative trial design approaches in m...

Human Drugs

Insys Gets Fast Track for Potential EpiPen Rival

FDA grants Insys Therapeutics a fast track designation for its epinephrine nasal spray as an investigational treatment for anaphylaxis.

Human Drugs

Pull Shared System REMS Guidance: NACDS

Chain drug stores urge FDA to withdraw a draft guidance on waivers for single, shared system REMS, and other stakeholders also critique it.

Human Drugs

CDER Statisticians Tout Flexible Trial Designs

An online CDER post describes work of Center statistical researchers in developing complex innovative clinical trial designs.

FDA Modernizing Regulation Approach: Gottlieb

FDA commissioner Scott Gottlieb says the agency is modernizing its approach to medical product regulation to support innovation in development of drug...

Human Drugs

Sexual Enhancement Product Permanent Injunction

The New Jersey federal court approves a permanent injunction sought by FDA against several companies and their executives charged with illegally selli...

Human Drugs

Auris Medical Get FDA Buy-in for Pivotal Trial

FDA approves Auris Medicals proposed choice of primary and secondary efficacy endpoints for a pivotal Phase 3 trial of AM-111 (brimapitide), an invest...

Human Drugs

FDA Approves 2 Merck HIV-1 Drugs

FDA approves two Merck NDAs for human immunodeficiency virus (HIV)-1 drugs Delstrigo and Pifeltro.

Human Drugs

Bipartisan Prescription Safety Alert Bill

Three House members introduce legislation to create a prescription drug safety alert system to give drug dispensers patient information that can help ...

Medical Devices

Researchers Urge Stricter Breakthrough Device Reviews

Researchers say FDA should issue time-limited breakthrough device approvals with mandated period review of a devices safety and effectiveness to be su...