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Human Drugs

FDA Steps to Reduce REMS Generic Drug Blocks

FDA issues two draft guidances to help prevent branded drug companies from using shared system REMS negotiations to block generic entry.

Human Drugs

FDA Wants More Drug Shortage Info

FDA commissioner Scott Gottlieb says the agency is looking for additional steps it can take to mitigate the effect of drug shortages and help prevent ...

Medical Devices

MicroVention PMA Approved for Aneurysm Device

FDA approves a MicroVention PMA for the LVIS and LVIS Jr. stents for stent-assisted coil embolization of intracranial aneurysms.

Human Drugs

Nektar NDA for Pain Drug with Reduced Euphoria

Nektar Therapeutics files an NDA for NKTR-181, an analgesic opioid molecule that the company says exhibits a reduced incidence of specific side effect...

Human Drugs

Draft Guide on ICH Q12 Drug Manufacturing Annex

FDA makes available an International Council for Harmonization draft guidance entitled Q12 Technical and Regulatory Considerations for Pharmaceutical ...

Human Drugs

FDA Grants Genea Biocells Orphan Drug Designation

FDA grants Genea Biocells an orphan drug designation for GBC0905 and its use in treating facioscapulohumeral muscular dystrophy.

Human Drugs

Drug Pressor Effect Guidance

FDA releases a draft guidance to help sponsors with the premarket assessment of a drugs effect on blood pressure.

Human Drugs

FDA Issues Drug Product Lifecycle ICH Guidance

FDA publishes an International Conference on Harmonization draft guidance on technical and regulatory considerations for drug product lifecycle manage...

Medical Devices

Bench Performance Test Report Guidance

FDA releases a draft guidance listing relevant information the agency wants included in complete test reports for non-clinical bench performance testi...

Medical Devices

11 Observations from Zimmer Inspection

FDA releases the FDA-483 with 11 observations from a Zimmer Biomet inspection.