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Federal Register

Guide on Toxicokinetics Q & A

Federal Register notice. FDA makes available a guidance entitled S3A Guidance: Note for Guidance on Toxicokinetics: The Assessment of Systemic Exposur...

Human Drugs

FDA Denies Mylan Advair Petition Without Comment

FDA denies without comment a Mylan petition asking it to impose conditions on approval of any ANDA citing Advair Diskus as the reference-listed drug.

Human Drugs

Sellas Gains Orphan Status for Multiple Myeloma Drug

FDA grants Sellas Life Sciences Group an orphan drug designation for its novel drug candidate, galinpepimut-S, for treating multiple myeloma.

Federal Register

Draft Guide on Urinary Tract Infections

Federal Register notice: FDA makes available a draft guidance entitled Uncomplicated Urinary Tract Infections: Developing Drugs for Treatment.

Human Drugs

Drug Applications Need SNOMED CT Nomenclature

FDA asks drug applicants to use SNOMED CT to characterize disease names for product indications.

Human Drugs

Astellas sNDA Approved for Overactive Bladder

FDA approves an Astellas Pharma supplemental NDA that seeks approval for the use of mirabegron in combination with solifenacin succinate 5 mg for trea...

Human Drugs

Orphan Drugs Slower to Develop, Launch: Study

A Tufts Center for the Study of Drug Development analysis shows that development time for orphan drugs is significantly longer than for all new drugs ...

Human Drugs

Toxicokinetics Guidance Q&A Out

FDA issues a question-and-answer document on microsampling as part of the assessment of systemic exposure in toxicity studies.

Human Drugs

FDA Issues Draft uUTI Guidance

FDA issues a draft guidance for sponsors developing drugs to treat uncomplicated urinary tract infections.

Human Drugs

Lawmakers Consider Easing Off-label Promotion: Report

Harvard Medical School researchers Michael Sinha and Arnold Kesselheim say advocates of reduced government oversight of off-label drug promotion are t...