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Biologics

Merck sBLA for Keytruda in Cervical Cancer Patients

FDA accepts for priority review a Merck supplemental BLA for Keytruda (pembrolizumab) for treating patients with advanced cervical cancer that is prog...

Medical Devices

Ways to Improve Least Burdensome Guidance Suggested

Stakeholders tell FDA ways it could improve a draft guidance on the least burdensome concept for medical device regulation.

Human Drugs

FDA Clinical Hold on Advaxis Cancer Study

FDA places on clinical hold an Advaxis IND for a Phase 1/2 combination study of axalimogene filolisbac with AstraZenecas Imfinzi (durvalumab) for trea...

Medical Devices

QS Violations at Laser Dental Innovations

FDA warns Laser Dental Innovations about Quality System violations in its manufacturing of dental handpieces and laser fiber optic surgical devices.

Human Drugs

Bill to Fight Illegal Opioid Imports

Rep. Frank Pallone introduces legislation to strength FDA authority to combat illegal opioid importation.

Medical Devices

13 QS Violations Found at Koreas Dexcowin Co.

FDA warns Koreas Dexcowin Co. about multiple Quality System violations in its manufacturing of portable dental diagnostic X-ray devices.

Human Drugs

Biocon FDA-483 Released

FDA issues an FDA-483 with six observations from an inspection at Biocon, a Malaysian sterile drug producer.

FDA General

Latest FDA Warning Letters

FDA releases its latest batch of Warning Letters that includes Dexcowin Co., Laser Dental Innovations and Quali-Controle & Quali-Controle.

Federal Register

Guidance on Assessing DNA Reactive (Mutagenic) Impurities

Federal Register notice: FDA makes available a guidance entitled M7(R1): Assessment and Control of Deoxyribonucleic Acid (DNA) Reactive (Mutagenic) Im...

Federal Register

DTC Study to Evaluate Adequate Provision for Non-Web Users

Federal Register notice: FDA seeks OMB approval for a new proposed information collection for a drug direct-to-consumer broadcast advertising study en...