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FDA General

Latest Federal Register Notices

FDA Review posts the Federal Register notices for the week ending 2/23/2018.

Federal Register

24 ANDA Approvals Withdrawn

Federal Regiser notice: FDA withdraws approval of 24 ANDAs from multiple applicants because the products are no longer marketed.

Human Drugs

10 Observations in Hospira FDA-483

FDA releases an FDA-483 issued after an inspection at a Hospira sterile drug manufacturing plant.

Human Drugs

Ways to Ease Drug Interchangeability Claims: Avalere

Avalere Health identifies three steps it says FDA can take to facilitate interchangeable biosimilar applications and approvals.

Human Drugs

FDA Finds 11 Problems at Bayer Facility

FDA releases an 11-item FDA-483 issued following an inspection at a Bayer Pharma plant in Germany.

Human Drugs

8 Inspection Observations at Indoco Remedies

FDA releases a FDA-483 following an Indoco Remedies, Goa, India, inspection with eight inspection observations.

Federal Register

Regulatory Review Period Determined for Zydelig

Federal Register notice: FDA has determined for patent extension purposes that the regulatory review period for ICOS Corp.'s Zydelig (idelalisib) is 2...

Human Drugs

Drug Substance Q11 Guidance Out

FDA publishes a question-and-answer document to clarify provisions of the harmonized Q11 guidance on development and manufacture of drug substances.

Human Drugs

FDA Approves KemPharm's Pain NDA

FDA approves a KemPharm NDA for Apadaz (benzhydrocodone, and acetaminophen) for the short-term (no more than 14 days) management of acute pain.

Human Drugs

Mallinckrodt NDA for Neonate Drug Under Review

FDA accepts for review a Mallinckrodt NDA for stannsoporfin, indicated for treating neonates at risk for developing severe hyperbilirubinemia, or seve...