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Human Drugs

Pilot Program on Model-Informed Drug Development

FDA unveils a pilot program to evaluate model-informed drug development approaches that could improve clinical trial efficiency and increase the proba...

Federal Register

Guide Next Generation Sequencing-based IVDs

Federal Register notice: FDA makes available a guidance on Considerations for Design, Development, and Analytical Validation of Next Generation Sequen...

Federal Register

Guide on Genetic Variant Databases for IVD Support

Federal Register notice: FDA makes available a final guidance entitled Use of Public Human Genetic Variant Databases to Support Clinical Validity for ...

Human Drugs

FDA Backpedals on Alkermes NDA Filing Rufusal

FDA rescinds an Alkermes refuse-to-file letter issued late last month on its NDA for ALKS 5461 (buprenorphine and samidorphan), an investigational dru...

FDA General

Latest Federal Register Notices

FDA Review posts the Federal Register notices for the week ending 4/13/2018.

Human Drugs

12 Observations in Celltrion FDA-483

FDA releases the FDA-483 detailing 12 observations from a 2017 inspection at Koreas Celltrion drug manufacturing facility.

Human Drugs

Final Guidance on Special Protocol Assessments

FDA posts a guidance on Special Protocol Assessment that provides drug manufacturers with information about the procedures and policies adopted by CDE...

Federal Register

Panel to Review Siga Tech Smallpox NDA

Federal Register notice: FDA announces a 5/1 Antimicrobial Drugs Advisory Committee meeting to discuss a Siga Technologies NDA for tecovirimat.

Federal Register

Info Collection Extension on Dispute Resolution

Federal Register notice: FDA submits for OMB approval an information collection extension for its Guidance for Industry on Formal Dispute Resolution: ...

Medical Devices

Guide on Ultrasonic Diathermy Device 510(k)s

FDA releases a final guidance on Policy Clarification and Premarket Notification [510(k)] Submissions for Ultrasonic Diathermy Devices.